RESEARCH AND PEOPLE

Main research topics at CRBA
- Portal vein arterialization in acute liver necrosis.
- Molecular genetics of colon cancer.
- JC virus in colorectal carcinogenesis.
- Bile salt transporters in cholestasis.
- Ursodeoxycholic acid and apoptosis in chronic hepatitis.
- Bile acid nuclear receptors.
- Entero-hepatic bile acid transport.
- Polymorphysms and mutations in monogenic and complex diseases.
- Genetic instability of prostate cancer.
- Biomolecular characterization of colorectal cancer.
- IKK to NF-kappaB signaling in innate and adaptive immune responses, cellular survival and cancer
- Notch genes in liver and prostate cancer malignant progression.
- Oxidative damage and DNA-repair in cancer stem cells.
- Genetic polymorfisms in cytochines as determinants of the progression of chronic hepatitis.
- Preservation of the reperfusion injury during liver transplantation.
- Physiopathology of sodium ritention in liver cirrhosis.
- Haematopoietic stem cells in the repair of acute toxic liver damage.
- The cannabinoid system in the genesis of obesity and endocrine diseases.
- Endocrine determinants of obesity: from molecular biology to analytical chemistry.
- Prevention of ischemia/reperfusion injury.
- Molecular genetics of apoptosis and inflammation following kidney transplantation.
- Bio & chemiluminescent bioanalytical methods for environmental monitoring.
- Bioluminescence resonance energy transfer (BRET) in the study of steroid receptors.
- Porphyrin and thiols monitoring in biological matrices.
- CYP2D6 CYP2E1 polymorphisms in benzene metabolism.
- Flt3 receptor molecular genetics in acute myeloid leukaemia.
- Cell immunotherapy in murine lymphoma.
- Molecular epidemiology and cancer risk.
- Gastrointestinal neurologic diseases and functional bowel disorders.
- Cancer stem cells
- Morphological & molecular aspects of skeletal muscle aging
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